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Dengfeng Li Selected Research

aziridonin 44

12/2018Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.
1/2018Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis.

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Dengfeng Li Research Topics

Disease

25Neoplasms (Cancer)
05/2024 - 01/2014
15Breast Neoplasms (Breast Cancer)
04/2024 - 01/2014
6Hepatocellular Carcinoma (Hepatoma)
04/2024 - 10/2020
5Fibrosis (Cirrhosis)
04/2024 - 01/2022
5Triple Negative Breast Neoplasms
12/2018 - 01/2015
4Neoplasm Metastasis (Metastasis)
07/2023 - 03/2017
2Pancreatic Neoplasms (Pancreatic Cancer)
05/2024 - 01/2023
2Liver Neoplasms (Liver Cancer)
07/2022 - 01/2022
2Carcinogenesis
06/2021 - 11/2018
2Inflammation (Inflammations)
10/2020 - 12/2018
2Glioblastoma (Glioblastoma Multiforme)
06/2020 - 01/2019
2Colorectal Neoplasms (Colorectal Cancer)
01/2018 - 03/2017
2Infections
11/2015 - 04/2009
1Adenocarcinoma
07/2023
1Hepatitis
05/2023
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2023
1Abscess
01/2022
1Dehydration (Water Stress)
06/2021
1Rheumatoid Arthritis
10/2020
1Margins of Excision
10/2020
1Bacterial Infections (Bacterial Infection)
07/2020
1Brain Neoplasms (Brain Tumor)
06/2020
1Cholangiocarcinoma
07/2019
1Dementia (Dementias)
01/2019
1Glioma (Gliomas)
01/2019
1Hypogonadism (Hypergonadotropic Hypogonadism)
01/2019
1Ataxia (Dyssynergia)
01/2019
1AIDS-Related Complex (ARC)
01/2019
1Cerebellar Ataxia and Hypogonadotropic Hypogonadism
01/2019
1Sepsis (Septicemia)
09/2015
1Papillary Thyroid Cancer
07/2015
1Thyroid Neoplasms (Thyroid Cancer)
01/2014

Drug/Important Bio-Agent (IBA)

11MicroRNAs (MicroRNA)IBA
07/2019 - 01/2014
5AlbuminsIBA
04/2024 - 01/2022
5Proteins (Proteins, Gene)FDA Link
06/2021 - 01/2015
3Ethiodized Oil (Ethiodol)FDA Link
07/2022 - 10/2020
3Phosphotransferases (Kinase)IBA
12/2018 - 01/2017
2BilirubinIBA
04/2024 - 11/2023
2CarbohydratesIBA
07/2023 - 01/2023
2AntigensIBA
07/2023 - 01/2023
2Cyclin D1IBA
07/2019 - 07/2018
2CyclinsIBA
07/2019 - 07/2018
2Small Untranslated RNAIBA
07/2019 - 01/2017
2oridoninIBA
12/2018 - 01/2018
2aziridonin 44IBA
12/2018 - 01/2018
2LuciferasesIBA
07/2018 - 05/2016
2Small Interfering RNA (siRNA)IBA
03/2017 - 01/2015
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
04/2024
1AnnexinsIBA
04/2024
1gadolinium ethoxybenzyl DTPAFDA Link
11/2023
1Bovine Serum AlbuminIBA
01/2023
1Amino AcidsFDA Link
01/2023
1Tyrosine (L-Tyrosine)FDA Link
01/2023
1Phenylalanine (L-Phenylalanine)FDA Link
01/2023
1Indocyanine Green (Cardio-Green)FDA LinkGeneric
01/2022
1Circular RNAIBA
01/2022
1Glycine (Aminoacetic Acid)FDA LinkGeneric
06/2021
1Arginine (L-Arginine)FDA Link
06/2021
1IntegrinsIBA
06/2021
1ferric ferrocyanide (Prussian blue)FDA Link
06/2021
1ferumoxtran-10 (ultrasmall superparamagnetic iron oxide)IBA
06/2021
1Aspartic Acid (Aspartate)FDA Link
06/2021
1Peptides (Polypeptides)IBA
06/2021
1CytokinesIBA
10/2020
1MetalsIBA
06/2020
1SolutionsIBA
06/2020
1Biomarkers (Surrogate Marker)IBA
11/2019
1FlavonoidsIBA
01/2019
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2019
1Beclin-1IBA
01/2019
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2019
1galanginIBA
01/2019
1Messenger RNA (mRNA)IBA
12/2018
1Estrogen ReceptorsIBA
07/2018
110,10'-dimethyl-9,9'-biacridinium (Lucigenin)IBA
01/2018
1Cisplatin (Platino)FDA LinkGeneric
01/2018
1macranthoidin BIBA
01/2018
1Superoxides (Superoxide)IBA
01/2018
1PlatinumIBA
01/2018
1Carrier Proteins (Binding Protein)IBA
01/2018
1Mechanistic Target of Rapamycin Complex 1IBA
03/2017
1Deoxyribonucleases (DNase)FDA Link
11/2015
1Gold Colloid (Colloidal Gold)IBA
09/2015
1Casein Kinase II (Casein Kinase 2)IBA
01/2014
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2014
1Protein Kinases (Protein Kinase)IBA
01/2014
1Focal Adhesion Protein-Tyrosine KinasesIBA
04/2009
1Fibronectins (Fibronectin)IBA
04/2009

Therapy/Procedure

7Therapeutics
10/2020 - 08/2017
3Hepatectomy
05/2023 - 07/2019
2Radiotherapy
05/2024 - 01/2023
2Computer-Assisted Surgery (Image Guided Surgery)
07/2022 - 01/2022
2Precision Medicine
11/2021 - 07/2020
1Neoadjuvant Therapy
07/2023
1Catheters
01/2022
1Lasers (Laser)
06/2021
1Drug Therapy (Chemotherapy)
01/2018